{
  "$schema": "https://json-schema.org/draft/2020-12/schema",
  "$id": "https://healtheart.ru/spec/cvd-patient/1/schema.json",
  "title": "Healtheart CVD Patient Exchange Document",
  "description": "Нативный формат обмена структурированными данными кардиологического случая.",
  "type": "object",
  "additionalProperties": false,
  "required": [
    "format",
    "format_version",
    "patient_data"
  ],
  "properties": {
    "format": {
      "const": "cvd-patient"
    },
    "format_version": {
      "const": 1
    },
    "patient_data": {
      "type": "object",
      "title": "Структурированные данные кардиологического случая",
      "additionalProperties": false,
      "properties": {
        "GENERAL_INFO": {
          "$ref": "#/$defs/GENERAL_INFO"
        },
        "COMPLAINTS": {
          "$ref": "#/$defs/COMPLAINTS"
        },
        "RISK_FACTORS": {
          "$ref": "#/$defs/RISK_FACTORS"
        },
        "PAST_EVENTS": {
          "$ref": "#/$defs/PAST_EVENTS"
        },
        "KNOWN_CVD_DIAGNOSES": {
          "$ref": "#/$defs/KNOWN_CVD_DIAGNOSES"
        },
        "PHYSICAL_EXAM": {
          "$ref": "#/$defs/PHYSICAL_EXAM"
        },
        "LABS_CBC": {
          "$ref": "#/$defs/LABS_CBC"
        },
        "LABS_BIOCHEM": {
          "$ref": "#/$defs/LABS_BIOCHEM"
        },
        "LABS_LIPIDS": {
          "$ref": "#/$defs/LABS_LIPIDS"
        },
        "LABS_CARDIAC_MARKERS": {
          "$ref": "#/$defs/LABS_CARDIAC_MARKERS"
        },
        "LABS_COAGULATION": {
          "$ref": "#/$defs/LABS_COAGULATION"
        },
        "ECG_AND_BP_MONITORING": {
          "$ref": "#/$defs/ECG_AND_BP_MONITORING"
        },
        "ECHOCARDIOGRAPHY": {
          "$ref": "#/$defs/ECHOCARDIOGRAPHY"
        },
        "FUNCTIONAL_TESTS": {
          "$ref": "#/$defs/FUNCTIONAL_TESTS"
        },
        "CORONARY_AND_VASCULAR_IMAGING": {
          "$ref": "#/$defs/CORONARY_AND_VASCULAR_IMAGING"
        },
        "DEVICES_AND_PROCEDURES": {
          "$ref": "#/$defs/DEVICES_AND_PROCEDURES"
        },
        "CURRENT_MEDICATIONS": {
          "$ref": "#/$defs/CURRENT_MEDICATIONS"
        },
        "SCORES_AND_CLASSES": {
          "$ref": "#/$defs/SCORES_AND_CLASSES"
        },
        "FINAL_DIAGNOSES": {
          "$ref": "#/$defs/FINAL_DIAGNOSES"
        },
        "MODEL_OUTPUT": {
          "$ref": "#/$defs/MODEL_OUTPUT"
        }
      }
    }
  },
  "$defs": {
    "GENERAL_INFO": {
      "type": "object",
      "title": "Общие сведения",
      "additionalProperties": false,
      "properties": {
        "Patient_ID": {
          "type": [
            "string",
            "null"
          ],
          "title": "ID случая"
        },
        "Full_name": {
          "type": [
            "string",
            "null"
          ],
          "title": "ФИО пациента"
        },
        "Sex": {
          "type": [
            "string",
            "null"
          ],
          "title": "Пол",
          "examples": [
            "male",
            "female",
            "other",
            "unknown"
          ],
          "x-healtheart-known-values": [
            "male",
            "female",
            "other",
            "unknown"
          ]
        },
        "Age": {
          "type": [
            "number",
            "null"
          ],
          "title": "Возраст, лет",
          "minimum": 0,
          "maximum": 120,
          "x-healtheart-unit": "лет"
        },
        "Height_cm": {
          "type": [
            "number",
            "null"
          ],
          "title": "Рост",
          "minimum": 80,
          "maximum": 230,
          "x-healtheart-unit": "cm"
        },
        "Weight_kg": {
          "type": [
            "number",
            "null"
          ],
          "title": "Масса",
          "minimum": 20,
          "maximum": 250,
          "x-healtheart-unit": "kg"
        },
        "BMI": {
          "type": [
            "number",
            "null"
          ],
          "title": "Индекс массы тела",
          "minimum": 5,
          "maximum": 90,
          "x-healtheart-unit": "kg/m²"
        }
      }
    },
    "COMPLAINTS": {
      "type": "object",
      "title": "Жалобы",
      "additionalProperties": false,
      "properties": {
        "Main_complaint": {
          "type": [
            "string",
            "null"
          ],
          "title": "Основная жалоба"
        },
        "Complaint_duration": {
          "type": [
            "string",
            "null"
          ],
          "title": "Длительность жалоб"
        },
        "Onset_context": {
          "type": [
            "string",
            "null"
          ],
          "title": "Контекст начала симптомов"
        }
      }
    },
    "RISK_FACTORS": {
      "type": "object",
      "title": "Факторы риска",
      "additionalProperties": false,
      "properties": {
        "Smoking_status": {
          "type": [
            "string",
            "null"
          ],
          "title": "Курение",
          "examples": [
            "never",
            "former",
            "current"
          ],
          "x-healtheart-known-values": [
            "never",
            "former",
            "current"
          ]
        },
        "Hypertension": {
          "type": [
            "string",
            "null"
          ],
          "title": "Артериальная гипертензия",
          "examples": [
            "yes",
            "no",
            "unknown"
          ],
          "x-healtheart-known-values": [
            "yes",
            "no",
            "unknown"
          ]
        },
        "Diabetes_mellitus": {
          "type": [
            "string",
            "null"
          ],
          "title": "Сахарный диабет",
          "examples": [
            "type1",
            "type2",
            "no",
            "unknown"
          ],
          "x-healtheart-known-values": [
            "type1",
            "type2",
            "no",
            "unknown"
          ]
        },
        "Dyslipidemia": {
          "type": [
            "string",
            "null"
          ],
          "title": "Дислипидемия",
          "examples": [
            "yes",
            "no",
            "unknown"
          ],
          "x-healtheart-known-values": [
            "yes",
            "no",
            "unknown"
          ]
        },
        "Obesity_or_Metabolic_syndrome": {
          "type": [
            "string",
            "null"
          ],
          "title": "Ожирение / метаболический синдром"
        },
        "Chronic_kidney_disease_stage": {
          "type": [
            "string",
            "null"
          ],
          "title": "ХБП, стадия"
        },
        "Family_history_early_CVD": {
          "type": [
            "string",
            "null"
          ],
          "title": "Семейный анамнез раннего ССЗ"
        },
        "Physical_activity_level": {
          "type": [
            "string",
            "null"
          ],
          "title": "Физическая активность"
        },
        "Alcohol_and_other_substances": {
          "type": [
            "string",
            "null"
          ],
          "title": "Алкоголь и другие вещества"
        }
      }
    },
    "PAST_EVENTS": {
      "type": "object",
      "title": "Анамнез и события",
      "additionalProperties": false,
      "properties": {
        "Prior_MI": {
          "type": [
            "string",
            "null"
          ],
          "title": "Перенесённый инфаркт миокарда"
        },
        "Prior_stroke_TIA": {
          "type": [
            "string",
            "null"
          ],
          "title": "Инсульт / ТИА в анамнезе"
        },
        "Prior_PE_DVT": {
          "type": [
            "string",
            "null"
          ],
          "title": "ТЭЛА / ТГВ в анамнезе"
        },
        "Prior_cardiac_surgeries": {
          "type": [
            "string",
            "null"
          ],
          "title": "Кардиохирургические операции"
        },
        "Prior_congenital_heart_defect_and_surgeries": {
          "type": [
            "string",
            "null"
          ],
          "title": "ВПС и операции"
        },
        "History_myocarditis_pericarditis": {
          "type": [
            "string",
            "null"
          ],
          "title": "Миокардиты / перикардиты"
        },
        "Other_major_diseases": {
          "type": [
            "string",
            "null"
          ],
          "title": "Другие важные заболевания"
        }
      }
    },
    "KNOWN_CVD_DIAGNOSES": {
      "type": "object",
      "title": "Известные сердечно-сосудистые диагнозы",
      "additionalProperties": false,
      "properties": {
        "Known_IHD": {
          "type": [
            "string",
            "null"
          ],
          "title": "Известная ИБС"
        },
        "Known_HF": {
          "type": [
            "string",
            "null"
          ],
          "title": "Хроническая сердечная недостаточность"
        },
        "Known_arrhythmias": {
          "type": [
            "string",
            "null"
          ],
          "title": "Аритмии"
        },
        "Known_valvular_disease": {
          "type": [
            "string",
            "null"
          ],
          "title": "Клапанные пороки"
        },
        "Known_aortic_or_peripheral_arterial_disease": {
          "type": [
            "string",
            "null"
          ],
          "title": "Аорта / периферические артерии"
        },
        "Known_pulmonary_hypertension": {
          "type": [
            "string",
            "null"
          ],
          "title": "Лёгочная гипертензия"
        },
        "Known_congenital_heart_disease": {
          "type": [
            "string",
            "null"
          ],
          "title": "Врожденные пороки сердца"
        }
      }
    },
    "PHYSICAL_EXAM": {
      "type": "object",
      "title": "Физикальный осмотр",
      "additionalProperties": false,
      "properties": {
        "Blood_pressure_right_systolic_mmHg": {
          "type": [
            "number",
            "null"
          ],
          "title": "АД справа, систолическое",
          "minimum": 40,
          "maximum": 300,
          "x-healtheart-unit": "mmHg"
        },
        "Blood_pressure_right_diastolic_mmHg": {
          "type": [
            "number",
            "null"
          ],
          "title": "АД справа, диастолическое",
          "minimum": 20,
          "maximum": 200,
          "x-healtheart-unit": "mmHg"
        },
        "Blood_pressure_left_systolic_mmHg": {
          "type": [
            "number",
            "null"
          ],
          "title": "АД слева, систолическое",
          "minimum": 40,
          "maximum": 300,
          "x-healtheart-unit": "mmHg"
        },
        "Blood_pressure_left_diastolic_mmHg": {
          "type": [
            "number",
            "null"
          ],
          "title": "АД слева, диастолическое",
          "minimum": 20,
          "maximum": 200,
          "x-healtheart-unit": "mmHg"
        },
        "Heart_rate_bpm": {
          "type": [
            "number",
            "null"
          ],
          "title": "ЧСС",
          "minimum": 20,
          "maximum": 250,
          "x-healtheart-unit": "beats/min"
        },
        "Resp_rate": {
          "type": [
            "number",
            "null"
          ],
          "title": "ЧДД",
          "minimum": 4,
          "maximum": 80,
          "x-healtheart-unit": "breaths/min"
        },
        "SpO2_room_air_percent": {
          "type": [
            "number",
            "null"
          ],
          "title": "SpO₂ на комнатном воздухе",
          "minimum": 40,
          "maximum": 100,
          "x-healtheart-unit": "%"
        },
        "Peripheral_edema": {
          "type": [
            "string",
            "null"
          ],
          "title": "Периферические отёки"
        },
        "Lung_auscultation": {
          "type": [
            "string",
            "null"
          ],
          "title": "Аускультация лёгких"
        },
        "Heart_auscultation": {
          "type": [
            "string",
            "null"
          ],
          "title": "Аускультация сердца"
        },
        "Peripheral_pulses": {
          "type": [
            "string",
            "null"
          ],
          "title": "Периферические пульсы"
        }
      }
    },
    "LABS_CBC": {
      "type": "object",
      "title": "Общий анализ крови",
      "additionalProperties": false,
      "properties": {
        "Hb_g_L": {
          "type": [
            "number",
            "null"
          ],
          "title": "Гемоглобин",
          "minimum": 20,
          "maximum": 250,
          "x-healtheart-unit": "g/L"
        },
        "WBC_10e9_L": {
          "type": [
            "number",
            "null"
          ],
          "title": "Лейкоциты",
          "minimum": 0,
          "maximum": 300,
          "x-healtheart-unit": "10^9/L"
        },
        "PLT_10e9_L": {
          "type": [
            "number",
            "null"
          ],
          "title": "Тромбоциты",
          "minimum": 0,
          "maximum": 2000,
          "x-healtheart-unit": "10^9/L"
        }
      }
    },
    "LABS_BIOCHEM": {
      "type": "object",
      "title": "Биохимия",
      "additionalProperties": false,
      "properties": {
        "Creatinine_umol_L": {
          "type": [
            "number",
            "null"
          ],
          "title": "Креатинин",
          "minimum": 0,
          "maximum": 3000,
          "x-healtheart-unit": "µmol/L"
        },
        "eGFR_ml_min_1_73m2": {
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            "null"
          ],
          "title": "Расчётная СКФ",
          "minimum": 0,
          "maximum": 200,
          "x-healtheart-unit": "mL/min/1.73m²"
        },
        "ALT_U_L": {
          "type": [
            "number",
            "null"
          ],
          "title": "АЛТ",
          "minimum": 0,
          "maximum": 5000,
          "x-healtheart-unit": "U/L"
        },
        "AST_U_L": {
          "type": [
            "number",
            "null"
          ],
          "title": "АСТ",
          "minimum": 0,
          "maximum": 5000,
          "x-healtheart-unit": "U/L"
        },
        "Na_mmol_L": {
          "type": [
            "number",
            "null"
          ],
          "title": "Натрий",
          "minimum": 80,
          "maximum": 200,
          "x-healtheart-unit": "mmol/L"
        },
        "K_mmol_L": {
          "type": [
            "number",
            "null"
          ],
          "title": "Калий",
          "minimum": 1,
          "maximum": 10,
          "x-healtheart-unit": "mmol/L"
        },
        "Mg_mmol_L": {
          "type": [
            "number",
            "null"
          ],
          "title": "Магний",
          "minimum": 0,
          "maximum": 5,
          "x-healtheart-unit": "mmol/L"
        },
        "Glucose_fasting_mmol_L": {
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            "number",
            "null"
          ],
          "title": "Глюкоза натощак",
          "minimum": 0,
          "maximum": 80,
          "x-healtheart-unit": "mmol/L"
        },
        "HbA1c_percent": {
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            "number",
            "null"
          ],
          "title": "HbA1c",
          "minimum": 0,
          "maximum": 25,
          "x-healtheart-unit": "%"
        }
      }
    },
    "LABS_LIPIDS": {
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      "title": "Липидный профиль",
      "additionalProperties": false,
      "properties": {
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          "type": [
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            "null"
          ],
          "title": "Общий холестерин",
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          "maximum": 30,
          "x-healtheart-unit": "mmol/L"
        },
        "LDL_mmol_L": {
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            "null"
          ],
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          "maximum": 30,
          "x-healtheart-unit": "mmol/L"
        },
        "HDL_mmol_L": {
          "type": [
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            "null"
          ],
          "title": "ЛПВП",
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          "maximum": 10,
          "x-healtheart-unit": "mmol/L"
        },
        "Triglycerides_mmol_L": {
          "type": [
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            "null"
          ],
          "title": "Триглицериды",
          "minimum": 0,
          "maximum": 50,
          "x-healtheart-unit": "mmol/L"
        }
      }
    },
    "LABS_CARDIAC_MARKERS": {
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      "title": "Кардиомаркеры",
      "additionalProperties": false,
      "properties": {
        "Troponin_ng_L": {
          "type": [
            "number",
            "null"
          ],
          "title": "Тропонин",
          "minimum": 0,
          "maximum": 1000000,
          "x-healtheart-unit": "ng/L"
        },
        "CKMB_U_L": {
          "type": [
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            "null"
          ],
          "title": "КФК-МВ",
          "minimum": 0,
          "maximum": 100000,
          "x-healtheart-unit": "U/L"
        },
        "NT_proBNP_pg_ml": {
          "type": [
            "number",
            "null"
          ],
          "title": "NT-proBNP",
          "minimum": 0,
          "maximum": 1000000,
          "x-healtheart-unit": "pg/mL"
        }
      }
    },
    "LABS_COAGULATION": {
      "type": "object",
      "title": "Коагулограмма",
      "additionalProperties": false,
      "properties": {
        "INR": {
          "type": [
            "number",
            "null"
          ],
          "title": "МНО / INR",
          "minimum": 0,
          "maximum": 20
        },
        "APTT_sec": {
          "type": [
            "number",
            "null"
          ],
          "title": "АЧТВ / APTT",
          "minimum": 0,
          "maximum": 300,
          "x-healtheart-unit": "s"
        }
      }
    },
    "ECG_AND_BP_MONITORING": {
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      "title": "ЭКГ и мониторирование",
      "additionalProperties": false,
      "properties": {
        "Resting_ECG_summary": {
          "type": [
            "string",
            "null"
          ],
          "title": "ЭКГ покоя, сводка"
        },
        "Holter_ECG_summary": {
          "type": [
            "string",
            "null"
          ],
          "title": "Холтер-ЭКГ, сводка"
        },
        "ABPM_summary": {
          "type": [
            "string",
            "null"
          ],
          "title": "СМАД, сводка"
        }
      }
    },
    "ECHOCARDIOGRAPHY": {
      "type": "object",
      "title": "Эхокардиография",
      "additionalProperties": false,
      "properties": {
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          "type": [
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            "null"
          ],
          "title": "КДР ЛЖ",
          "minimum": 0,
          "maximum": 150,
          "x-healtheart-unit": "mm"
        },
        "LVESD_mm": {
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          ],
          "title": "КСР ЛЖ",
          "minimum": 0,
          "maximum": 150,
          "x-healtheart-unit": "mm"
        },
        "LVEF_percent": {
          "type": [
            "number",
            "null"
          ],
          "title": "ФВ ЛЖ",
          "minimum": 0,
          "maximum": 100,
          "x-healtheart-unit": "%"
        },
        "LA_diameter_mm": {
          "type": [
            "number",
            "null"
          ],
          "title": "Диаметр ЛП",
          "minimum": 0,
          "maximum": 120,
          "x-healtheart-unit": "mm"
        },
        "RV_diameter_mm": {
          "type": [
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            "null"
          ],
          "title": "Диаметр ПЖ",
          "minimum": 0,
          "maximum": 120,
          "x-healtheart-unit": "mm"
        },
        "PASP_mmHg": {
          "type": [
            "number",
            "null"
          ],
          "title": "PASP",
          "minimum": 0,
          "maximum": 200,
          "x-healtheart-unit": "mmHg"
        },
        "IVS_thickness_mm": {
          "type": [
            "number",
            "null"
          ],
          "title": "Толщина МЖП",
          "minimum": 0,
          "maximum": 50,
          "x-healtheart-unit": "mm"
        },
        "PW_LV_thickness_mm": {
          "type": [
            "number",
            "null"
          ],
          "title": "Задняя стенка ЛЖ",
          "minimum": 0,
          "maximum": 50,
          "x-healtheart-unit": "mm"
        },
        "Mitral_valve_area_cm2": {
          "type": [
            "number",
            "null"
          ],
          "title": "Площадь митрального клапана",
          "minimum": 0,
          "maximum": 20,
          "x-healtheart-unit": "cm²"
        },
        "Aortic_valve_area_cm2": {
          "type": [
            "number",
            "null"
          ],
          "title": "Площадь аортального клапана",
          "minimum": 0,
          "maximum": 20,
          "x-healtheart-unit": "cm²"
        },
        "Valvular_regurgitation": {
          "type": [
            "string",
            "null"
          ],
          "title": "Клапанные регургитации"
        },
        "Pericardial_effusion": {
          "type": [
            "string",
            "null"
          ],
          "title": "Перикардиальный выпот"
        }
      }
    },
    "FUNCTIONAL_TESTS": {
      "type": "object",
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